Cargando…

2844. Butyrogenic Bacteria After Acute Graft vs. Host Disease Associate with the Development of Steroid Refractory GVHD

BACKGROUND: Steroid refractory acute graft- vs. -host-disease (GVHD) after hematopoietic cell transplantation (HCT) is highly morbid with limited treatment options. Murine studies show protection from GVHD with butyrate exposure but direct exposure of stem/progenitor cells to butyrate inhibits colon...

Descripción completa

Detalles Bibliográficos
Autores principales: Golob, Jonathan L, DeMeules, Martha M, Loeffelholz, Tillie, Quinn, Z Z, Dame, Michael K, Silvestri, Sabrina, Wu, Michael, Schmidt, Tom, Fiedler, Tina L, Hoostal, Matthew, Mielcarek, Marco, Spence, Jason, Pergam, Steven A, Fredricks, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808863/
http://dx.doi.org/10.1093/ofid/ofz359.149