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2844. Butyrogenic Bacteria After Acute Graft vs. Host Disease Associate with the Development of Steroid Refractory GVHD
BACKGROUND: Steroid refractory acute graft- vs. -host-disease (GVHD) after hematopoietic cell transplantation (HCT) is highly morbid with limited treatment options. Murine studies show protection from GVHD with butyrate exposure but direct exposure of stem/progenitor cells to butyrate inhibits colon...
Autores principales: | Golob, Jonathan L, DeMeules, Martha M, Loeffelholz, Tillie, Quinn, Z Z, Dame, Michael K, Silvestri, Sabrina, Wu, Michael, Schmidt, Tom, Fiedler, Tina L, Hoostal, Matthew, Mielcarek, Marco, Spence, Jason, Pergam, Steven A, Fredricks, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808863/ http://dx.doi.org/10.1093/ofid/ofz359.149 |
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