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97. Competition Experiments for the Baloxavir-Resistant I38T Influenza A Mutant

BACKGROUND: Baloxavir marboxil (BXM), a cap-dependent endonuclease inhibitor, has been recently approved in the United States for the treatment of influenza infections. It is superior to oseltamivir for reducing the time of viral shedding but is reported to have a low barrier of resistance. We sough...

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Detalles Bibliográficos
Autores principales: Checkmahomed, Liva, Mhamdi, Zeineb, Carbonneau, Julie, Baz, Mariana, Abed, Yacine, Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808909/
http://dx.doi.org/10.1093/ofid/ofz359.021