1725. Shear Forces Induce a Transient, Calcineurin-Dependent Hyper-Virulent Phenotype in Mucorales via Soluble Factors

BACKGROUND: Myocutaneous mucormycosis is encountered in settings of extreme mechanical forces such as combat-related blast injuries or natural catastrophes. It is unclear whether the virulence of Mucorales is affected by mechano-biological factors such as shear forces (SF). METHODS: Spores of clinic...

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Detalles Bibliográficos
Autores principales: Wurster, Sebastian, Tatara, Alexander M, Albert, Nathaniel D, Mikos, Antonios G, Ibrahim, Ashraf S, Bruno, Vincent M, Kontoyiannis, Dimitrios P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809355/
http://dx.doi.org/10.1093/ofid/ofz360.1588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809355/
http://dx.doi.org/10.1093/ofid/ofz360.1588

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