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1725. Shear Forces Induce a Transient, Calcineurin-Dependent Hyper-Virulent Phenotype in Mucorales via Soluble Factors
BACKGROUND: Myocutaneous mucormycosis is encountered in settings of extreme mechanical forces such as combat-related blast injuries or natural catastrophes. It is unclear whether the virulence of Mucorales is affected by mechano-biological factors such as shear forces (SF). METHODS: Spores of clinic...
Autores principales: | Wurster, Sebastian, Tatara, Alexander M, Albert, Nathaniel D, Mikos, Antonios G, Ibrahim, Ashraf S, Bruno, Vincent M, Kontoyiannis, Dimitrios P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809355/ http://dx.doi.org/10.1093/ofid/ofz360.1588 |
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