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1544. Efficacy of Human-Simulated Cefiderocol Exposure Against Gram-Negative Bacteria in an Iron-Overloaded Murine Thigh Infection Model
BACKGROUND: Cefiderocol (CFDC) is a siderophore-cephalosporin conjugate which exploits bacterial iron scavenging in reaction to the hypoferremic response of host immunity and achieves potent in vivo activity against various Gram-negative bacteria (GNB). In patients with hereditary or iatrogenic hemo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809466/ http://dx.doi.org/10.1093/ofid/ofz360.1408 |