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2784. Increased Frontal Lobe Volume and Density in Macaques Exposed to Zika Virus In Utero

BACKGROUND: In utero Zika virus (ZIKV) infection causes birth defects and neurodevelopmental deficits in neonates. We reasoned that a translational macaque model of congenital ZIKV infection could define disease pathophysiology not possible in human clinical studies. METHODS: We inoculated 5 pregnan...

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Detalles Bibliográficos
Autores principales: Mohr, Emma L, Koenig, Michelle, Razo, Elaina, Mitzey, Ann, Semler, Matt, Stewart, Laurel, Breitbach, Meghan, Newman, Christina, Dudley, Dawn, Weiler, Andrea, Rybarczyk, Sierra, Bach, Kathryn, Mohns, Mariel, Simmons, Heather, Mejia, Andres, Teixeira, Leandro, Schotzko, Michele, Nork, T Michael, Rasmussen, Carol, Katz, Alex, Hou, Jiancheng, Hartman, Amy, Hoeve, James Ver, Kim, Charlene, Schneider, Mary, Ausderau, Karla, Kohn, Sarah, Aliota, Matthew, Salamat, M Shahriar, Hayes, Jennifer, Schultz-Darken, Nancy, Antony, Kathleen, Noguchi, Kevin, Zeng, Xiankun, Ikonomidou, Chrysanthy, Prabhakaran, Vivek, Capuano III, Saverio, Friedrich, Thomas, Golos, Thaddeus, O’Connor, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809508/
http://dx.doi.org/10.1093/ofid/ofz360.2461