231. Microbial cell-free DNA Sequencing to Detect Borrelia burgdorferi DNA in the Plasma of Pediatric Patients with Lyme Disease

BACKGROUND: Diagnosing Lyme disease often involves laboratory evaluation, yet available tests have limitations. Serology remains negative for weeks after infection occurs, and may then remain positive for years. Borrelia burgdorferi blood PCR testing has low sensitivity, rendering it unhelpful. We s...

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Detalles Bibliográficos
Autores principales: Handel, Andrew S, Ho, Carine, Hollemon, Desiree D, Hong, David K, Beneri, Christy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809588/
http://dx.doi.org/10.1093/ofid/ofz360.306