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Phylodynamic theory of persistence, extinction and speciation of rapidly adapting pathogens

Rapidly evolving pathogens like influenza viruses can persist by changing their antigenic properties fast enough to evade the adaptive immunity, yet they rarely split into diverging lineages. By mapping the multi-strain Susceptible-Infected-Recovered model onto the traveling wave model of adapting p...

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Detalles Bibliográficos
Autores principales: Yan, Le, Neher, Richard A, Shraiman, Boris I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809594/
https://www.ncbi.nlm.nih.gov/pubmed/31532393
http://dx.doi.org/10.7554/eLife.44205