Cargando…
Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry
Identifying neurons that have functional opioid receptors is fundamental for the understanding of the cellular, synaptic and systems actions of opioids. Current techniques are limited to post hoc analyses of fixed tissues. Here we developed a fluorescent probe, naltrexamine-acylimidazole (NAI), to l...
Autores principales: | Arttamangkul, Seksiri, Plazek, Andrew, Platt, Emily J, Jin, Haihong, Murray, Thomas F, Birdsong, William T, Rice, Kenner C, Farrens, David L, Williams, John T |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809603/ https://www.ncbi.nlm.nih.gov/pubmed/31589142 http://dx.doi.org/10.7554/eLife.49319 |
Ejemplares similares
-
Functional independence of endogenous μ- and δ-opioid receptors co-expressed in cholinergic interneurons
por: Arttamangkul, Seksiri, et al.
Publicado: (2021) -
Ligand-directed labeling of opioid receptors for covalent attachment of fluorophores or small-molecule probes
por: Adoff, Hayden, et al.
Publicado: (2023) -
Cellular tolerance at the µ-opioid receptor is phosphorylation dependent
por: Arttamangkul, Seksiri, et al.
Publicado: (2018) -
The Endogenous Opioid Met-Enkephalin Modulates Thalamo-Cortical Excitation Inhibition Balance in a Medial Thalamus-Anterior Cingulate Cortex Circuit
por: Hervert, Erwin Arias, et al.
Publicado: (2023) -
Synthesis of Enantiopure 10-Nornaltrexones
in the
Search for Toll-like Receptor 4 Antagonists and Opioid Ligands
por: Selfridge, Brandon R., et al.
Publicado: (2014)