1569. A Translational Model to Assess the Impact of Polymyxin B Dose Fractionation on Kidney Injury

BACKGROUND: Progression of antimicrobial resistance has revived Polymyxin B (PB) use in clinical practice. Dose-dependent acute kidney injury (AKI) limits its clinical use. It is unclear whether dose fractionation of total daily dose can lessen kidney injury. We assessed the role of PB fractionation...

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Detalles Bibliográficos
Autores principales: Liu, Jiajun, Pais, Gwendolyn M, Avedissian, Sean N, Lee, Andrew, Rhodes, Nathaniel J, Hauser, Alan R, Scheetz, Marc H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809707/
http://dx.doi.org/10.1093/ofid/ofz360.1433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809707/
http://dx.doi.org/10.1093/ofid/ofz360.1433

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