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2770. Intrapulmonary Vaccination with an M Protein-Deficient Respiratory Syncytial Virus (RSV) Vaccine Protects Infant Baboons Against an RSV Challenge
BACKGROUND: RSV infection is a major cause of lung disease in infants, yet there is no licensed vaccine. We are developing a live RSV vaccine with a deletion of the M protein (“Mnull RSV”). The RSV M protein is responsible for assembling newly synthesized RSV proteins into intact virus. Mnull RSV in...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809773/ http://dx.doi.org/10.1093/ofid/ofz360.2447 |