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1566. Population Pharmacokinetics of Voriconazole: Serum Albumin Status as a Novel Marker of Clearance and Dosage Optimization

BACKGROUND: Voriconazole (VRCZ) is a first-line agent for the treatment of invasive aspergillosis. In this study, we report the first study on population pharmacokinetics (PPK) of VRCZ in Thai patients. METHODS: A PPK study was performed by combining blood VRCZ data from intensive pharmacokinetic (P...

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Detalles Bibliográficos
Autores principales: Chantharit, Prawat, Tantasawat, Montira, Kasai, Hidefumi, Tanigawara, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809812/
http://dx.doi.org/10.1093/ofid/ofz360.1430