439. Iclaprim Use for Acute Bacterial Skin and Skin Structure Infection (ABSSSI) is Not Associated with Hyperkalemia: Phase 3 REVIVE Studies

BACKGROUND: Trimethoprim inhibits sodium channels in the distal portion of the renal tubule, thereby impairing renal potassium excretion. Trimethoprim has been associated with a greater risk of hyperkalemia compared with other antibiotics (amoxicillin, nitrofurantoin, cefalexin, ciprofloxacin). An a...

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Detalles Bibliográficos
Autores principales: Huang, David B, Noviello, Stephanie S, Lodise, Thomas, McKinnell, James, Dwyer, Jamie P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809937/
http://dx.doi.org/10.1093/ofid/ofz360.512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809937/
http://dx.doi.org/10.1093/ofid/ofz360.512

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