2604. Changes in a Fatty Acid Kinase Associated with Daptomycin (DAP) Resistance Lead to Increased Collagen Binding and Biofilm Formation in Enterococcus faecalis

BACKGROUND: Enterococci are a major cause of healthcare-associated infections with limited treatment options. We previously identified that mutations in dak (a gene encoding a putative fatty acid kinase), ace (a collagen adhesin) and the YxdJK stress response system are associated with DAP resistanc...

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Detalles Bibliográficos
Autores principales: Miller, William R, Singh, Kavindra V, Reyes, Jinnethe, Murray, Barbara E, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810061/
http://dx.doi.org/10.1093/ofid/ofz360.2282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810061/
http://dx.doi.org/10.1093/ofid/ofz360.2282

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