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2109. Liposomal Amphotericin B-associated Nephrotoxicity in Obese and Non-obese Patients

BACKGROUND: Liposomal amphotericin B (L-amb) is an important antifungal agent which exhibits significant rates of dose-dependent nephrotoxicity. Animal studies demonstrate only small amounts of L-amb distribute into adipose tissue and obese animals show greater risk of nephrotoxicity with L-amb admi...

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Detalles Bibliográficos
Autores principales: Tritle, Brandon, Peterson, Logan, Olson, Jared, Benefield, Emily, Cariello, Paloma F, Benefield, Russell J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810171/
http://dx.doi.org/10.1093/ofid/ofz360.1789