Resolution metabolomes activated by hypoxic environment

Targeting hypoxia-sensitive pathways in immune cells is of interest in treating diseases. Here, we demonstrate that physiologic hypoxia (1% O(2)), as encountered in bone marrow and spleen, accelerates human M2 macrophage efferocytosis of apoptotic-neutrophils and senescent erythrocytes via lipolysis...

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Detalles Bibliográficos
Autores principales: Norris, Paul C., Libreros, Stephania, Serhan, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810174/
https://www.ncbi.nlm.nih.gov/pubmed/31681846
http://dx.doi.org/10.1126/sciadv.aax4895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810174/
https://www.ncbi.nlm.nih.gov/pubmed/31681846
http://dx.doi.org/10.1126/sciadv.aax4895

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