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Lack of Efficacy of High-Titered Immunoglobulin in Patients with West Nile Virus Central Nervous System Disease

West Nile Virus (WNV) can result in clinically severe neurologic disease. There is no treatment for WNV infection, but administration of anti-WNV polyclonal human antibody has demonstrated efficacy in animal models. We compared Omr-IgG-am, an immunoglobulin product with high titers of anti-WNV antib...

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Detalles Bibliográficos
Autores principales: Gnann, John W., Agrawal, Amy, Hart, John, Buitrago, Martha, Carson, Paul, Hanfelt-Goade, Diane, Tyler, Ken, Spotkov, Jared, Freifeld, Alison, Moore, Thomas, Reyno, Jorge, Masur, Henry, Jester, Penelope, Dale, Ilet, Li, Yufeng, Aban, Inmaculada, Lakeman, Fred D., Whitley, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810207/
https://www.ncbi.nlm.nih.gov/pubmed/31625835
http://dx.doi.org/10.3201/eid2511.190537