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2712. Safety and Immunogenicity of two Doses of ExPEC4V Vaccine Against Extraintestinal Pathogenic Escherichia coli Disease in Healthy Adult Participants

BACKGROUND: The ExPEC4V vaccine contains 4 Escherichia coli O-antigens (O1A, O2, O6A, O25B) conjugated to exotoxin protein A and is being studied for prevention of Invasive Extraintestinal pathogenic E. coli (ExPEC) Disease (IED). This phase-2 double-blind study assessed safety and immunogenicity of...

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Detalles Bibliográficos
Autores principales: B Smith, William, Abbanat, Darren, Spiessens, Bart, Go, Oscar, Haazen, Wouter, de Rosa, Tiziano, Fae, Kellen, Poolman, Jan, Thoelen, Stefan, de Palacios, Patricia Ibarra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810236/
http://dx.doi.org/10.1093/ofid/ofz360.2389