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2764. Generation of a Balanced, Tetravalent Dengue Vaccine Based on Contemporary Strains Using a Computational, Synthetic Biology-Based Platform

BACKGROUND: The WHO estimates that there may be 50 million cases of dengue virus (DENV) infection worldwide every year. There is no safe vaccine against DENV licensed in the United States. The development of a balanced and effective anti-DENV vaccine is vital to preventing morbidity and mortality. C...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Stauft, Charles B, Raviprakash, Kanakatte, Coleman, J Robert, Mueller, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810340/
http://dx.doi.org/10.1093/ofid/ofz360.2441