Building sensory axons: Delivery and distribution of Na(V)1.7 channels and effects of inflammatory mediators

Sodium channel Na(V)1.7 controls firing of nociceptors, and its role in human pain has been validated by genetic and functional studies. However, little is known about Na(V)1.7 trafficking or membrane distribution along sensory axons, which can be a meter or more in length. We show here with single-...

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Detalles Bibliográficos
Autores principales: Akin, Elizabeth J., Higerd, Grant P., Mis, Malgorzata A., Tanaka, Brian S., Adi, Talia, Liu, Shujun, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810356/
https://www.ncbi.nlm.nih.gov/pubmed/31681845
http://dx.doi.org/10.1126/sciadv.aax4755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810356/
https://www.ncbi.nlm.nih.gov/pubmed/31681845
http://dx.doi.org/10.1126/sciadv.aax4755

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