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Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation

The characteristics of DNA methylation changes that occur during neurogenesis in vivo remain unknown. We used whole-genome bisulfite sequencing to quantitate DNA cytosine modifications in differentiating neurons and their progenitors isolated from mouse brain at the peak of embryonic neurogenesis. L...

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Detalles Bibliográficos
Autores principales: Hahn, Maria A., Jin, Seung-Gi, Li, Arthur X., Liu, Jiancheng, Huang, Zhijun, Wu, Xiwei, Kim, Byung-Wook, Johnson, Jennifer, Bilbao, Adrienne-Denise V., Tao, Shu, Yim, Jacob A., Fong, Yuman, Goebbels, Sandra, Schwab, Markus H., Lu, Qiang, Pfeifer, Gerd P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810389/
https://www.ncbi.nlm.nih.gov/pubmed/31681843
http://dx.doi.org/10.1126/sciadv.aax0080