2651. Protection Against Human Cytomegalovirus Acquisition Is Associated with IgG Binding to Cell-Associated CMV glycoprotein B in Two Historical gB/MF59 Vaccine Cohorts

BACKGROUND: Human cytomegalovirus (CMV) is the most common congenital infection worldwide. A CMV glycoprotein B (gB) subunit vaccine with MF59 adjuvant achieved ~50% protection in phase II clinical trials in postpartum and adolescent women. Interestingly, postpartum vaccinees showed poor virus neutr...

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Detalles Bibliográficos
Autores principales: Jenks, Jennifer A, Nelson, Cody S, Pass, Robert F, Bernstein, David I, Roark, Hunter K, Chan, Cliburn, Permar, Sallie R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810453/
http://dx.doi.org/10.1093/ofid/ofz360.2329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810453/
http://dx.doi.org/10.1093/ofid/ofz360.2329

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