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1548. Characterizing Cefepime Neurotoxicity: Experience from a Tertiary Care Center Performing β-lactam Therapeutic Drug Monitoring

BACKGROUND: Based on prior studies, elderly patients and those with renal dysfunction are prone to cefepime (CFP) toxicity. The toxicokinetics and toxicodynamics for CFP are not well established. Lamoth et al. reported a 50% probability of CFP neurotoxicity at a serum trough concentration of ≥22 mg/...

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Detalles Bibliográficos
Autores principales: Nys, Cara, Hurst, Natalie, Liu, Jiajun, Cherabuddi, Kartikeya, Iovine, Nicole M, Scheetz, Marc H, Rhodes, Nathaniel J, Klinker, Kenneth, Veena, Venugopalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810473/
http://dx.doi.org/10.1093/ofid/ofz360.1412