Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria

A decline of skeletal muscle strength with aging is a primary cause of mobility loss and frailty in older persons, but the molecular mechanisms of such decline are not understood. Here, we performed quantitative proteomic analysis from skeletal muscle collected from 58 healthy persons aged 20 to 87...

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Detalles Bibliográficos
Autores principales: Ubaida-Mohien, Ceereena, Lyashkov, Alexey, Gonzalez-Freire, Marta, Tharakan, Ravi, Shardell, Michelle, Moaddel, Ruin, Semba, Richard D, Chia, Chee W, Gorospe, Myriam, Sen, Ranjan, Ferrucci, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810669/
https://www.ncbi.nlm.nih.gov/pubmed/31642809
http://dx.doi.org/10.7554/eLife.49874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810669/
https://www.ncbi.nlm.nih.gov/pubmed/31642809
http://dx.doi.org/10.7554/eLife.49874

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