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609. Differing Genotypic Contexts Between E. coli and A. baumannii Modulate the Role of blaADC-7 in the Development of Antibiotic Collateral Sensitivity

BACKGROUND: Antibiotic resistance is a global health crisis. While persistent drug discovery of novel antibiotics has previously been relied upon to thwart resistance, evolution inevitably perseveres. While genes conferring antibiotic resistance have previously been characterized, it is unclear how...

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Detalles Bibliográficos
Autores principales: McClure, Erin, Newman, Julia, Krishnan, Nikhil, Rutter, Joseph, Hujer, Andrea M, Adams, Mark D, Scott, Jacob, Bonomo, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810876/
http://dx.doi.org/10.1093/ofid/ofz360.678