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727. Potency of the β-Lactamase Inhibitor QPX7728 Is Minimally Affected by KPC Mutations that Reduce Potency of Ceftazidime–Avibactam

BACKGROUND: In the United States, carbapenem-resistant Enterobacteriaceae (CRE) are mainly represented by KPC-producing strains and ceftazidime–avibactam (C/A) is increasingly used to treat infections caused by KPC-producers. C/A resistant (C/A-R) mutants with mutations in bla(KPC) can be isolated i...

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Detalles Bibliográficos
Autores principales: Lomovskaya, Olga, Nelson, Kirk J, Rubio-Aparicio, Debora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810935/
http://dx.doi.org/10.1093/ofid/ofz360.795