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601. TelA and XpaC Are Novel Mediators of Daptomycin Resistance in Enterococcus faecium

BACKGROUND: The YycFG system is an essential two-component regulatory system involved in cell wall homeostasis associated with the development of daptomycin (DAP) resistance in E. faecium. Importantly, the standard combination of DAP plus β-lactam is ineffective against strains harboring mutations i...

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Detalles Bibliográficos
Autores principales: Tran, Truc T, Panesso, Diana, Diaz, Lorena, Rios, Rafael, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811118/
http://dx.doi.org/10.1093/ofid/ofz360.670