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689. Therapeutic Efficacy of CB-012, a Novel Cloudbreak Antiviral Fc-Conjugate (AVC) in Lethal Mouse Models of Influenza A (H1N1) and Influenza B (Victoria)

BACKGROUND: In 2018, the World Health Organization estimated up to 650,000 influenza-related respiratory deaths occur annually. Cidara therapeutics is developing a novel class of potent, long-acting antiviral Fc-conjugates (AVCs) against influenza that in a single molecule combine a surface-acting a...

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Detalles Bibliográficos
Autores principales: Levin, James, Borchardt, Allen, Lam, Thanh, Jiang, Wanlong, Chen, Zhi-Yong, Fortier, Joanne, Akers-Rodriguez, Suzanne, Amundson, Karin, Donatelli, Joanna, Döhrmann, Simon, Cole, Jason, Tari, Les
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811134/
http://dx.doi.org/10.1093/ofid/ofz360.757