613. Suppression of Daptomycin Resistance Development in Staphylococcus aureus Is a Class Effect of β-Lactams and Is Independent of Daptomycin–β Lactam Synergy

BACKGROUND: Previous studies demonstrate that adding oxacillin during daptomycin (DAP) exposure can prevent DAP resistance development in community-acquired (ST8/USA300) MRSA, presumably by preventing mprF mutation. Hospital-acquired strains, such as MRSA sequence types 5 and 239, typically have hig...

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Detalles Bibliográficos
Autores principales: Miller, Christopher R, Dey, Somrita, Smolenski, Paula, Kulkarni, Pushkar S, Baines, Sarah L, David. Berti, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811192/
http://dx.doi.org/10.1093/ofid/ofz360.682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811192/
http://dx.doi.org/10.1093/ofid/ofz360.682

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