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624. Molecular Characterization of Baseline Enterobacteriaceae and Pseudomonas aeruginosa from a Phase 3 Nosocomial Pneumonia (ASPECT-NP) Clinical Trial

BACKGROUND: ASPECT-NP, a phase 3, randomized, double-blind, multicenter trial, evaluated ceftolozane/tazobactam (C/T) 3 g q8h vs. meropenem 1 g q8h for 8–14 days in adults for treatment of ventilated nosocomial pneumonia. Baseline Gram-negative (GN) isolates from patients were tested for mechanisms...

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Detalles Bibliográficos
Autores principales: Castanheira, Mariana, Johnson, Matthew G, Yu, Brian, Huntington, Jennifer A, Carmelitano, Patricia, Bruno, Christopher, Rhee, Elizabeth G, Motyl, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811271/
http://dx.doi.org/10.1093/ofid/ofz360.692