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667. Preclinical Pharmacokinetic and Pharmacodynamic Characterization of EDP-938, a Novel and Potent NonFusion Replication Inhibitor of Respiratory Syncytial Virus

BACKGROUND: Respiratory syncytial virus (RSV) infection presents a significant health challenge in young children, elderly and immunocompromised patients. To date, there are no effective treatments available. EDP-938 was designed to meet this unmet medical need and is currently in Phase 2 clinical t...

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Detalles Bibliográficos
Autores principales: Jiang, Li-Juan, Xu, Lisha, Huang, Meng, Zhang, Shucha, Li, Yang, Zang, Indy, Kibel, Jonathan, Adams, Madison, Labrecque, Noelle, Rhodin, Michael, McAllister, Nicole, Lin, Kai, Jong Kim, In, Sun Or, Yat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811274/
http://dx.doi.org/10.1093/ofid/ofz360.735