The expression of the insulin receptor in gastric cancer correlates with the HER2 status and may have putative therapeutic implications

BACKGROUND: Metabolic reprogramming in gastric cancer (GC) involves not only an alteration of glucose metabolism, but also of insulin receptor (IR) expression. We investigated if (1) GCs express the IR in cancer cells (CC-IR) and vasculature (VIR), (2) IR expression is clinically relevant and may be...

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Detalles Bibliográficos
Autores principales: Heckl, Steffen M., Wiesener, Viva, Behrens, Hans-Michael, Ulase, Dita, Krüger, Sandra, Röcken, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811372/
https://www.ncbi.nlm.nih.gov/pubmed/30989432
http://dx.doi.org/10.1007/s10120-019-00964-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811372/
https://www.ncbi.nlm.nih.gov/pubmed/30989432
http://dx.doi.org/10.1007/s10120-019-00964-6

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