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Epithelial EP4 plays an essential role in maintaining homeostasis in colon
Colonic epithelial cells comprise the mucosal barrier, and their dysfunction promotes microbial invasion from the gut lumen and induces the development of intestinal inflammation. The EP4 receptor is known to mediate the protective effect of prostaglandin (PG) E(2) in the gastrointestinal tract; how...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811535/ https://www.ncbi.nlm.nih.gov/pubmed/31645712 http://dx.doi.org/10.1038/s41598-019-51639-2 |