Epithelial EP4 plays an essential role in maintaining homeostasis in colon

Colonic epithelial cells comprise the mucosal barrier, and their dysfunction promotes microbial invasion from the gut lumen and induces the development of intestinal inflammation. The EP4 receptor is known to mediate the protective effect of prostaglandin (PG) E(2) in the gastrointestinal tract; how...

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Detalles Bibliográficos
Autores principales: Matsumoto, Yoshihide, Nakanishi, Yuki, Yoshioka, Takuto, Yamaga, Yuichi, Masuda, Tomonori, Fukunaga, Yuichi, Sono, Makoto, Yoshikawa, Takaaki, Nagao, Munemasa, Araki, Osamu, Ogawa, Satoshi, Goto, Norihiro, Hiramatsu, Yukiko, Breyer, Richard M., Fukuda, Akihisa, Seno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811535/
https://www.ncbi.nlm.nih.gov/pubmed/31645712
http://dx.doi.org/10.1038/s41598-019-51639-2

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