Enhanced hexosamine metabolism drives metabolic and signaling networks involving hyaluronan production and O-GlcNAcylation to exacerbate breast cancer

The hexosamine biosynthetic pathway (HBP) metabolically regulates dynamic cellular events by linking nutrient availability to numerous signaling networks. Significant alterations in the HBP are often associated with cancer pathogenesis. In this study, we investigated the molecular events underlying...

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Detalles Bibliográficos
Autores principales: Chokchaitaweesuk, Chatchadawalai, Kobayashi, Takashi, Izumikawa, Tomomi, Itano, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811536/
https://www.ncbi.nlm.nih.gov/pubmed/31645543
http://dx.doi.org/10.1038/s41419-019-2034-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811536/
https://www.ncbi.nlm.nih.gov/pubmed/31645543
http://dx.doi.org/10.1038/s41419-019-2034-y

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