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Minute-scale persistence of a GPCR conformation state triggered by non-cognate G protein interactions primes signaling
Despite the crowded nature of the cellular milieu, ligand–GPCR–G protein interactions are traditionally viewed as spatially and temporally isolated events. In contrast, recent reports suggest the spatial and temporal coupling of receptor–effector interactions, with the potential to diversify downstr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811539/ https://www.ncbi.nlm.nih.gov/pubmed/31645561 http://dx.doi.org/10.1038/s41467-019-12755-9 |