Cardiac Pacemaker Cells Generate Cardiomyocytes from Fibroblasts in Long-Term Cultures

Because cardiomyocyte generation is limited, the turnover of cardiomyocytes in adult heart tissues is much debated. We report here that cardiac pacemaker cells can generate cardiomyocytes from fibroblasts in vitro. Sinoatrial node cells (SANCs) were isolated from adult guinea pig hearts and were cul...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiuchi, Shigeki, Usami, Akino, Shimoyama, Tae, Otsuka, Fuminori, Yamaguchi, Sachiko, Nakamura, Tomonori, Suzuki, Shigeto, Ono, Kageyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811548/
https://www.ncbi.nlm.nih.gov/pubmed/31645588
http://dx.doi.org/10.1038/s41598-019-51001-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811548/
https://www.ncbi.nlm.nih.gov/pubmed/31645588
http://dx.doi.org/10.1038/s41598-019-51001-6

Ejemplares similares