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Cardiac Pacemaker Cells Generate Cardiomyocytes from Fibroblasts in Long-Term Cultures
Because cardiomyocyte generation is limited, the turnover of cardiomyocytes in adult heart tissues is much debated. We report here that cardiac pacemaker cells can generate cardiomyocytes from fibroblasts in vitro. Sinoatrial node cells (SANCs) were isolated from adult guinea pig hearts and were cul...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811548/ https://www.ncbi.nlm.nih.gov/pubmed/31645588 http://dx.doi.org/10.1038/s41598-019-51001-6 |