A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing

Macroautophagy, a key player in protein quality control, is proposed to be systematically impaired in distinct tissues and causes coordinated disruption of protein homeostasis and ageing throughout the body. Although tissue-specific changes in autophagy and ageing have been extensively explored, the...

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Detalles Bibliográficos
Autores principales: Zhou, Yifei, Wang, Xueqing, Song, Mengjiao, He, Zhidong, Cui, Guizhong, Peng, Guangdun, Dieterich, Christoph, Antebi, Adam, Jing, Naihe, Shen, Yidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811558/
https://www.ncbi.nlm.nih.gov/pubmed/31645592
http://dx.doi.org/10.1038/s41467-019-12821-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811558/
https://www.ncbi.nlm.nih.gov/pubmed/31645592
http://dx.doi.org/10.1038/s41467-019-12821-2

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