Cargando…

A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing

Macroautophagy, a key player in protein quality control, is proposed to be systematically impaired in distinct tissues and causes coordinated disruption of protein homeostasis and ageing throughout the body. Although tissue-specific changes in autophagy and ageing have been extensively explored, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Yifei, Wang, Xueqing, Song, Mengjiao, He, Zhidong, Cui, Guizhong, Peng, Guangdun, Dieterich, Christoph, Antebi, Adam, Jing, Naihe, Shen, Yidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811558/ https://www.ncbi.nlm.nih.gov/pubmed/31645592 http://dx.doi.org/10.1038/s41467-019-12821-2

Ejemplares similares

Ageing induces tissue‐specific transcriptomic changes in Caenorhabditis elegans
por: Wang, Xueqing, et al.
Publicado: (2022)

Comments on ‘Molecular architecture of lineage allocation and tissue organization in early mouse embryo’
por: Cui, Guizhong, et al.
Publicado: (2019)

Genetics of Aging in Caenorhabditis elegans
por: Antebi, Adam
Publicado: (2007)

Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans
por: Heestand, Bree N., et al.
Publicado: (2013)

Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans
por: Wiese, Mary, et al.
Publicado: (2010)

Hypoxia disrupts proteostasis in Caenorhabditis elegans
por: Fawcett, Emily M, et al.
Publicado: (2015)

Guidelines for monitoring autophagy in Caenorhabditis elegans
por: Zhang, Hong, et al.
Publicado: (2015)

Approaches for Studying Autophagy in Caenorhabditis elegans
por: Chen, Yanfang, et al.
Publicado: (2017)

Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development
por: Bratic, Ivana, et al.
Publicado: (2009)

Nanoparticulate air pollution disrupts proteostasis in Caenorhabditis elegans
por: Garcia Manriquez, Bailey A., et al.
Publicado: (2023)

Spatiotemporal regulation of autophagy during Caenorhabditis elegans aging
por: Chang, Jessica T, et al.
Publicado: (2017)

Disruption of mitochondrial dynamics affects behaviour and lifespan in Caenorhabditis elegans
por: Byrne, Joseph J., et al.
Publicado: (2019)

Proteome changes of Caenorhabditis elegans upon a Staphylococcus aureus infection
por: Bogaerts, Annelies, et al.
Publicado: (2010)

Glucosamine Extends the Lifespan of Caenorhabditis elegans via Autophagy Induction
por: Shintani, Tomoya, et al.
Publicado: (2018)

Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegans
por: O'Toole, Eileen T., et al.
Publicado: (2003)

Neonicotinoid-containing insecticide disruption of growth, locomotion, and fertility in Caenorhabditis elegans
por: Bradford, Beatrix R., et al.
Publicado: (2020)

C-KIT Expression Distinguishes Fetal from Postnatal Skeletal Progenitors
por: He, Di Demi, et al.
Publicado: (2020)

Caenorhabditis Elegans
Publicado: (2000)

Divergent gene expression in the conserved dauer stage of the nematodes Pristionchus pacificus and Caenorhabditis elegans
por: Sinha, Amit, et al.
Publicado: (2012)

RNA interference may result in unexpected phenotypes in Caenorhabditis elegans
por: De-Souza, Evandro A, et al.
Publicado: (2019)

Lung development and regeneration: newly defined cell types and progenitor status
por: Meng, Xiaogao, et al.
Publicado: (2023)

The application of traditional transmission electron microscopy for autophagy research in Caenorhabditis elegans
por: Kovács, Attila L.
Publicado: (2015)

Molecular Basis of Neuronal Autophagy in Ageing: Insights from Caenorhabditis elegans
por: Konstantinidis, Georgios, et al.
Publicado: (2021)

High-Dose Irradiation Inhibits Motility and Induces Autophagy in Caenorhabditis elegans
por: Yamasaki, Akira, et al.
Publicado: (2021)

Autophagy Regulation Influences β-Amyloid Toxicity in Transgenic Caenorhabditis elegans
por: Lin, Hongru, et al.
Publicado: (2022)

LGG-1/GABARAP lipidation is not required for autophagy and development in Caenorhabditis elegans
por: Leboutet, Romane, et al.
Publicado: (2023)

Distinct effects of tubulin isotype mutations on neurite growth in Caenorhabditis elegans
por: Zheng, Chaogu, et al.
Publicado: (2017)

Distinct pathways for export of silencing RNA in Caenorhabditis elegans systemic RNAi
por: Yoshida, Keita, et al.
Publicado: (2023)

Disruption of insulin signalling preserves bioenergetic competence of mitochondria in ageing Caenorhabditis elegans
por: Brys, Kristel, et al.
Publicado: (2010)

Identification of A Novel Link between the Intermediate Filament Organizer IFO-1 and Cholesterol Metabolism in the Caenorhabditis elegans Intestine
por: A. Coch, Richard, et al.
Publicado: (2020)

Verapamil extends lifespan in Caenorhabditis elegans by inhibiting calcineurin activity and promoting autophagy
por: Liu, Wenwen, et al.
Publicado: (2020)

The Nucleolus of Caenorhabditis elegans
por: Lee, Li-Wei, et al.
Publicado: (2012)

Immunometabolism in Caenorhabditis elegans
por: Anderson, Sarah M., et al.
Publicado: (2020)

Immunosenescence in Caenorhabditis elegans
por: Kim, Sieun S., et al.
Publicado: (2022)

Oogenesis in Caenorhabditis elegans
por: Davis, Gregory M., et al.
Publicado: (2023)

SUN-050 The Evolutionarily Conserved Function of COUP-TF Genes in the Differentiation of Photoreceptor Cells in the Retina
por: Zhu, Jian, et al.
Publicado: (2019)

Distinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans
por: Lewis, John A, et al.
Publicado: (2009)

Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans
por: Ghosh, Rajarshi, et al.
Publicado: (2012)

Correction for Distinct effects of tubulin isotype mutations on neurite growth in Caenorhabditis elegans
Publicado: (2017)

Proteasome activity contributes to pro-survival response upon mild mitochondrial stress in Caenorhabditis elegans
por: Sladowska, Maria, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7q83ekrs1fu1dge4d79879i9nu