Structural analysis of biological targets by host:guest crystal lattice engineering

To overcome the laborious identification of crystallisation conditions for protein X-ray crystallography, we developed a method where the examined protein is immobilised as a guest molecule in a universal host lattice. We applied crystal engineering to create a generic crystalline host lattice under...

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Detalles Bibliográficos
Autores principales: Ernst, Patrick, Plückthun, Andreas, Mittl, Peer R. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811568/
https://www.ncbi.nlm.nih.gov/pubmed/31645583
http://dx.doi.org/10.1038/s41598-019-51017-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811568/
https://www.ncbi.nlm.nih.gov/pubmed/31645583
http://dx.doi.org/10.1038/s41598-019-51017-y

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