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Structural analysis of biological targets by host:guest crystal lattice engineering
To overcome the laborious identification of crystallisation conditions for protein X-ray crystallography, we developed a method where the examined protein is immobilised as a guest molecule in a universal host lattice. We applied crystal engineering to create a generic crystalline host lattice under...
Autores principales: | Ernst, Patrick, Plückthun, Andreas, Mittl, Peer R. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811568/ https://www.ncbi.nlm.nih.gov/pubmed/31645583 http://dx.doi.org/10.1038/s41598-019-51017-y |
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