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Mithramycin A Inhibits Colorectal Cancer Growth by Targeting Cancer Stem Cells

The pivotal role of cancer initiating stem cells (CSCs) in tumor initiation, growth, metastasis and drug resistance has led to the postulation of a ‘total cancer therapy’ paradigm, which involves targeting both cancer cells and CSCs for effective therapy. However, the progress in identifying drugs f...

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Detalles Bibliográficos
Autores principales: Quarni, Waise, Dutta, Rinku, Green, Ryan, Katiri, Sandhyabanu, Patel, Bhaumik, Mohapatra, Shyam S., Mohapatra, Subhra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811578/
https://www.ncbi.nlm.nih.gov/pubmed/31645574
http://dx.doi.org/10.1038/s41598-019-50917-3