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Mithramycin A Inhibits Colorectal Cancer Growth by Targeting Cancer Stem Cells
The pivotal role of cancer initiating stem cells (CSCs) in tumor initiation, growth, metastasis and drug resistance has led to the postulation of a ‘total cancer therapy’ paradigm, which involves targeting both cancer cells and CSCs for effective therapy. However, the progress in identifying drugs f...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811578/ https://www.ncbi.nlm.nih.gov/pubmed/31645574 http://dx.doi.org/10.1038/s41598-019-50917-3 |