Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation

Resistin is a key cytokine associated with metabolic and inflammatory diseases. Especially in East Asian populations, the expression levels are strongly influenced by genetic polymorphisms. Mechanisms and functional implications of this genetic control are still unknown. By employing reporter assays...

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Detalles Bibliográficos
Autores principales: Kumar, Dilip, Lee, Bernett, Puan, Kia Joo, Lee, Wendy, Luis, Boris San, Yusof, Nurhashikin, Andiappan, Anand Kumar, Del Rosario, Ricardo, Poschmann, Jeremie, Kumar, Pavanish, DeLibero, Gennaro, Singhal, Amit, Prabhakar, Shyam, De Yun, Wang, Poidinger, Michael, Rötzschke, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811637/
https://www.ncbi.nlm.nih.gov/pubmed/31645609
http://dx.doi.org/10.1038/s41598-019-51592-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811637/
https://www.ncbi.nlm.nih.gov/pubmed/31645609
http://dx.doi.org/10.1038/s41598-019-51592-0

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