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Estimating numbers of intracellular molecules through analysing fluctuations in photobleaching

The impact of fluorescence microscopy has been limited by the difficulties of expressing measurements of fluorescent proteins in numbers of molecules. Absolute numbers enable the integration of results from different laboratories, empower mathematical modelling, and are the bedrock for a quantitativ...

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Detalles Bibliográficos
Autores principales: Bakker, Elco, Swain, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811640/
https://www.ncbi.nlm.nih.gov/pubmed/31645577
http://dx.doi.org/10.1038/s41598-019-50921-7