Concerted dynamics of metallo-base pairs in an A/B-form helical transition

Metal-mediated base pairs expand the repertoire of nucleic acid structures and dynamics. Here we report solution structures and dynamics of duplex DNA containing two all-natural C-Hg(II)-T metallo base pairs separated by six canonical base pairs. NMR experiments reveal a 3:1 ratio of well-resolved s...

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Detalles Bibliográficos
Autores principales: Schmidt, Olivia P., Jurt, Simon, Johannsen, Silke, Karimi, Ashkan, Sigel, Roland K. O., Luedtke, Nathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811676/
https://www.ncbi.nlm.nih.gov/pubmed/31645548
http://dx.doi.org/10.1038/s41467-019-12440-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811676/
https://www.ncbi.nlm.nih.gov/pubmed/31645548
http://dx.doi.org/10.1038/s41467-019-12440-x

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