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Impact of atherosclerotic disease on cerebral microvasculature and tissue oxygenation in awake LDLR−/−hApoB+/+ transgenic mice

We explore cortical microvasculature changes during the progression of atherosclerosis using young and old transgenic atherosclerotic (ATX) mice with thinned-skull cranial window. In awake animals, exploiting intrinsic signal optical imaging, Doppler optical coherence tomography, and two-photon micr...

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Detalles Bibliográficos
Autores principales: Lu, Yuankang, Zhang, Cong, Lu, Xuecong, Moeini, Mohammad, Thorin, Eric, Lesage, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811703/
https://www.ncbi.nlm.nih.gov/pubmed/31673566
http://dx.doi.org/10.1117/1.NPh.6.4.045003