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PRDX2 protects against oxidative stress induced by H. pylori and promotes resistance to cisplatin in gastric cancer

Helicobacter pylori (H. pylori) infection is the main risk factor for gastric cancer. The role of antioxidant enzyme peroxiredoxin 2 (PRDX2) in gastric tumorigenesis remains unknown. In vitro (AGS and SNU-1 cell lines) and in vivo mouse models were utilized to investigate the role of PRDX2 in respon...

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Detalles Bibliográficos
Autores principales: Wang, Sen, Chen, Zheng, Zhu, Shoumin, Lu, Heng, Peng, Dunfa, Soutto, Mohammed, Naz, Huma, Peek, Richard, Xu, Hao, Zaika, Alexander, Xu, Zekuan, El-Rifai, Wael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811995/
https://www.ncbi.nlm.nih.gov/pubmed/31536951
http://dx.doi.org/10.1016/j.redox.2019.101319